Retatrutide is a novel triple hormone receptor agonist, targeting GLP-1 (Glucagon-Like Peptide-1), GIP (Glucose-Dependent Insulinotropic Polypeptide), and glucagon receptors. This multi-pathway activity positions Retatrutide as a potential next-generation agent in metabolic research, particularly in the fields of obesity, insulin resistance, and type 2 diabetes.
Early-stage clinical studies have shown promising effects on body weight reduction, appetite suppression, and metabolic regulation, making it a molecule of high interest in endocrine and metabolic research.
Key Research Highlights:
Multi-agonist mechanism for potential synergistic metabolic effects
Investigated for its role in weight loss and glucose control
Extended half-life for once-weekly dosing in trial models
Structurally related to peptide-based therapies like tirzepatide
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